Ergothioneine Improves Memory & Sleep in Older Adults Cognitive decline is common in older people. A still little discussed nutrient found in mushrooms, ergothioneine, might help. Ergothioneine is a vitamin-like amino acid found most abundantly in mushrooms. Evidence is mounting that, because of its antioxidant, inflammation regulating and detoxifying properties, ergothioneine may powerfully promote longevity. Studies show that ergothioneine levels are lower in elderly people with mild cognitive impairment. North Americans may not get enough ergothioneine in their diet. When Americans