Pistachios

Pistachios Are a Natural Source of Melatonin. How Well Does it Work?

A surprising discovery is that several plants and herbs are natural sources of melatonin, a hormone produced in the pineal gland. Pistachios are one of these natural sources.

Melatonin is widely used to support healthy sleep. This study compared a pistachio-derived melatonin supplement with a synthetic melatonin supplement, with both groups receiving 1 mg of melatonin.

Researchers found that pistachio-derived melatonin was absorbed just as well as the synthetic version.

It also worked equally well. Participants experienced significant improvements in:

• Falling asleep faster
• Total sleep time
• Sleep quality
• Feeling refreshed upon waking

This study highlights pistachio-derived melatonin as another natural option for supporting healthy sleep.

Food and Nutrition Sciences. October 10, 2025;16(10):1427–1439.

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